Therapies : currently therapies for Glycoprotein Storage Diseases are primarily supportive or palliative in nature. However, bone marrow and cord blood transplantation have shown initial success for patients with Alpha-Mannosidosis, Fucosidosis and, potentially, Mucolipidosis II. Enzyme Replacement Therapy is currently available for a few LSD's and is being explored for Alpha-Mannosidosis.

Bone Marrow & Cord Blood Transplants

• BMT FAQ: The University of Minnesota's resource for bone marrow transplants
• BMT Resources: Information assembled for the lay person by a five-time transplant recipient
• Center for International Blood and Marrow Transplant Research
• Cord Blood Donor Foundation
• Genetic Disease Treatment Options: University of California San Francisco transplant program's information on options for Lysosomal Diseases
• National Cord Blood Program
• National Marrow Donor Program
• Robert's Road to Recovery: Kathleen King's online journal about her son, Robert's, two transplants for Alpha-Mannosidosis.
• Ronald McDonald House Charities: Ronald McDonald Houses provide housing support internationally for families with a relative receiving a transplant
• Transplant Center Search: find a North American transplant center via BMT Infonet
• TransWeb

Enzyme Replacement Therapy (ERT)

• Efficacy of ERT In Mice with Alpha-Mannosidosis
• The Hue-Man Project: A European collaborative effort to develop an effective enzyme replacement therapy for Alpha-Mannosidosis
• Zymenex: Scandinavian biopharmaceutical company currently engaged in the late stage pre-clinical development of a pharmaceutical intervention for Alpha-Mannosidosis

Pamidronate

• ISMRD's Pamidronate Page
• Medline
• Osteodystrophy of Mucolipidosis Type III (pdf)