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Spectrum of Mutations in Alpha Mannosidosis Patients

An extraction from Spectrum of mutations in a-mannosidosis by Thomas Berg, Hilde Monica Frostad Riise, Gaute Martin Hansen, Dag Malm, Lisbeth Tranebjaerg, Ole Kristian Tollersrud and Øivind Nilssen.  American Journal of Genetics, January 1999.


see also: Geographic Map of Patient Mutations

legend:

 
Patient Ethnicity Mutation on Allele 1 Mutation on Allele 2 Sources
1a Dutch W77X ND O. P. van Diggelen, Rotterdam
2a,b Dutch 1076-1077insA 1076-1077insA R. Wevers, Nijmegen, The Netherlands; Jansen et al. (1987)
3a,b Dutch R750W ND O. P. van Diggelen, Rotterdam
4a Finnish IVS14+1G->C IVS14+1G->C M. Renlund, Helsinki
5a Finnish R750Wc R750Wc M. Renlund, Helsinki
6a,b Finnish R750W ND GM00654;d Autio et al. (1973)
7a Finnish R750Wc ND M. Renlund, Helsinki
8a French (Reunion) 935delAT 935delAT E. Vamos, Brussels; Farriaux et al. (1975)
9a,b French (Reunion) IVS17 +1G->A IVS17 +1G->A C. Largillière, Lille, France; Farriaux et al. (1975)
10a,b German Y359X IVS11-3del125 M. Beck, Mainz, Germany
11a,b German Y359X IVS7+2T->G,E402K M. Beck, Mainz, Germany; Spranger et al. (1976)
12b German 1815delA IVS14+1G->C M. Beck, Mainz, Germany; Gehler et al. (1975)
13 German R750Wc ND M. Beck, Mainz, Germany
14a,b Greek IVS5-1G->Cc ND H. Michelakakis, Athens
15A Italian IVS12+2T->Gc IVS12+2T->Gc R. Gitzelmann and N. U. Bosshard, Zurich
15B Italian IVS12+2T->Gc IVS12+2T->Gc R. Gitzelmann and N. U. Bosshard, Zurich
16 Italian T355P IVS17+1G->T R. Gatti, Genoa
17a Italian IVS17+1G->T ND R. Gatti, Genoa; Cerruti Mainardi et al. (1982)
18a Italian R750W R750W B. Bertagnolio, Milan
19a,b Norwegian 1153-1154insCCc 1153-1154insCCc D. Malm and L. Tranebjærg, Tromsø, Norway; Malm et al. (1995)
20Aa,b Norwegian 1153-1154insCCc IVS14-2A->Gc D. Malm and L. Tranebjærg, Tromsø, Norway; Malm et al. (1995)
20Bb Norwegian 1153-1154insCCc IVS14-2A->Gc D. Malm and L. Tranebjærg, Tromsø, Norway; Malm et al. (1995)
21Ab Norwegian IVS14-2A->Gc IVS14-2A->Gc D. Malm and L. Tranebjærg, Tromsø, Norway
21Bb Norwegian IVS14-2A->Gc IVS14-2A->Gc D. Malm and L. Tranebjærg, Tromsø, Norway
22a Norwegian IVS14+1G->Cc L809Pc D. Malm and L. Tranebjærg, Tromsø, Norway
23a,b Polish R750W R750W O. P. van Diggelen, Rotterdam
24a,b Polish R750W ND B. Czartoryska, Warsaw
25a Polish R750W ND B. Czartoryska, Warsaw
26a Polish R750W ND B. Czartoryska, Warsaw
27a,b Spanish W714R W714R E. Vamos, Brussels; Loeb et al. (1969)
28b Spanish E563X E563X A. Chabàs and M. J. Coll, Barcelona
29b Swedish R750W L809P J.-E. Månsson, Mølndal, Sweden
30a,b Swedish L809P L809P J.-E. Månsson, Mølndal, Sweden
31a,b Turkish R750W R750W O. P. van Diggelen and J. G. N. de Jong, Rotterdam; Jansen et al. (1987)
32a,b Caucasian P356R P356R GM04518d
33a,b Caucasian R750W R750W GM02817d

 


Page title: Spectrum of Mutations in Alpha Mannosidosis
URL: http://www.mannosidosis.org/alphaman/mutations.htm
Editor:
Dag Malm; Webmaster: Paul Murphy
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